Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
應用:
A labelled form of XL518 (X746250), a potent, selective, orally bioavailable inhibitor of MEK1, a component of the RAS/RAF/MEK/ERK pathway. It inhibits proliferation and stimulates apoptosis in a variety of human tumor cell lines.
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