Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
Regorafenib N-Demethyl-N-4-(3-fluoro-4-methylphenoxy)-N-methylpicolinamide is an impurity of Regorafenib (R143000), which inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.
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