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產品基本信息

產品編號：H804508

產品名稱：21-Hydroxyeplerenone (α, β mixture)

產品CAS：334678-67-0

規格含量：1mg

產品價格：面議

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產品詳細介紹

標準品編號:	H804508
名稱:	21-Hydroxyeplerenone (α, β mixture)
別名:	(7α,?11α,?17α)?-9,?11-?Epoxy-?17,?21-?dihydroxy-?3-?oxo-?γ-?lactone Methyl Ester Pregn-?4-?ene-?7,?21-?dicarboxylic Acid
CAS號:	334678-67-0
參考CAS號:	Î²-isomer: 1633889-97-0
分子式:	C??H??O?
外觀:	白色固體
熔點:	>223°C (dec.)
分子量:	430.49
儲存:	冰箱, under inert atmosphere
溶解度:	Chloroform (Slightly), Methanol (Slightly)
種類:	Standards; Chiral Molecules;
應用:	21-Hydroxyeplerenone is a metabolite of Eplerenone (E588775), which is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure. 21-Hydroxyeplerenone is a metabolite of eplerenone in humans and dogs.
參考文獻	de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005); Cook C., et al.: Drug Metab. Dispos., 30, 1344 (2002);

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