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產(chǎn)品基本信息
產(chǎn)品編號(hào)：T895530
產(chǎn)品名稱：TRV-130 Hydrochloric Acid Salt
產(chǎn)品CAS：1401031-39-7
規(guī)格含量：25mg
產(chǎn)品價(jià)格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
T895530
名稱:
TRV-130 Hydrochloric Acid Salt
別名:
TRV130 Hydrochloride; (R)-N-((3-methoxythiophen-2-yl)methyl)-2-(9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)ethanamine Hydrochloride
CAS號(hào):
1401031-39-7
參考CAS號(hào):
1401028-24-7 free amine
分子式:
C??H??ClN?O?S
外觀:
白色固體
熔點(diǎn):
白色固體
分子量:
423.01
儲(chǔ)存:
-20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Slightly)
類別:
Standards; Chiral Molecules;
應(yīng)用:
TRV-130 is a μ-opioid receptor (MOR) G protein-biased ligand. It is potently analgesic while causing less gastrointestinal dysfunction and respiratory suppression than morphine at equianalgesic doses.
參考文獻(xiàn)
DeWire, S., et al.: J. Pharm. Exper. Ther., 344, 708 (2013); Soergel, D., et al.: Pain, 155, 1829 (2014)
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