產(chǎn)品基本信息
產(chǎn)品編號：P165800
產(chǎn)品名稱：(S,S)-Palonosetron Hydrochloride
產(chǎn)品CAS：135729-62-3
規(guī)格含量：1g
產(chǎn)品價格：面議
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產(chǎn)品詳細介紹
標準品編號:
P165800
名稱:
(S,S)-Palonosetron Hydrochloride
別名:
(3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one Hydrochloride; Aloxi; Onicit; RS-25259-197
CAS號:
135729-62-3
參考CAS號:
Free cmpd: 135729-61-2
分子式:
C??H??N?O • (HCl)
外觀:
白色至白色固體
熔點:
238 - 244°C
分子量:
296.413646
儲存:
冰箱
溶解度:
Methanol (Slightly, Heated), Water (Slightly)
類別:
Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
應用:
(S,S)-Palonosetron Hydrochloride is a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
參考文獻
Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),
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