Lamivudine (R)-S-Oxide; 4-Amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; [2R-(2α,3β,5α)]-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone S-Oxide; 1,3-Oxathiolane, 2(1H)-pyrimidinone Deriv.; [2R-(2α,3β,5α)]-4-Amino-1-[2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; GI 138870X; Lamivudine EP Impurity H
雜質(zhì):
Lamivudine EP Impurity H
CAS號:
160552-54-5
參考CAS號:
(3S)-isomer: 160552-55-6
分子式:
C?H??N?O?S
外觀:
白色固體
熔點(diǎn):
>230°C (dec.)
分子量:
245.26
儲存:
Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Water (Slightly, heated)
種類:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
Lamivudine (R)-Sulfoxide (Lamivudine EP Impurity H) is a metabolite of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.
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