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產(chǎn)品基本信息
產(chǎn)品編號(hào)：E320302
產(chǎn)品名稱：EB 47-d8
產(chǎn)品CAS：
規(guī)格含量：10mg
產(chǎn)品價(jià)格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
E320302
名稱:
EB 47-d8
別名:
5'-Deoxy-5'-[4-[2-[(2,3-dihydro-1-oxo-1H-isoindol-4-yl)amino]-2-oxoethyl]-1-piperazinyl]-5'-oxoadenosine-d8; 4-[1-(6-Amino-9H-purin-9-yl)-1-deoxy-β-D- ribofuranuronoyl]-N-(2,3-dihydro-1-oxo-1H-isoindol-4-yl)-1-piperazineacetamide-d8
參考CAS:
366454-36-6 unlabelled
分子式:
C??H??D?N?O?
分子量:
545.58
種類:
Research Tools;
應(yīng)用:
Isotope labelled EB 47 is a potent inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1). Poly(ADP-ribose) polymerases (PARPs) play a major role in cellular survival and maintenance of energy stores after genotoxic insult.
參考文獻(xiàn)
Jagtap, et al.: Bioorg. Med. Chem. Lett., 14, 81 (2004), Gaymes, et al.: Haematologica, 94, 638 (2009), Ferraris, et al.: J. Med. Chem. 53, 4561 (2010),
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