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產品基本信息
產品編號：I666650
產品名稱：Intedanib
產品CAS：656247-17-5
規格含量：25 mg
產品價格：面議
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產品詳細介紹
標準品編號:
I666650
名稱:
Intedanib
別名:
(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-H-Indole-6-carboxylic Acid Methyl Ester; BIBF 1120; Ofev; Vargatef; Nintedanib
CAS號:
656247-17-5
分子式:
C??H??N?O?
外觀:
Light Yellow to Light Green Solid
熔點:
>237ºC (dec.)
分子量:
539.62
儲存:
冰箱
溶解度:
DMSO (Slightly), Methanol (Slightly)
種類:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用:
It is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. An antitumor agent.
參考文獻
Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)
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