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產品基本信息

產品編號：T774540

產品名稱：7-{[(2,2,2,-Trichloroethyl)oxy]carbonyl} Baccatin III (4S, 5S)-3-Benzoyl-2-(4-methoxypheny

產品CAS：1033574-06-9

規格含量：1mg

產品價格：面議

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產品詳細介紹

標準品編號:	T774540
名稱:	7-{[(2,2,2,-Trichloroethyl)oxy]carbonyl} Baccatin III (4S, 5S)-3-Benzoyl-2-(4-methoxyphenyl)-4-phenyl-5-oxazolidinecarboxylate
別名:	(4S,5S)-3-Benzoyl-2-(4-methoxyphenyl)-4-phenyl-(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[[(2,2,2-trichloroethoxy)carbonyl]oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester 5-Oxazolidinecarboxylic Acid
CAS號:	1033574-06-9
分子式:	C??H??Cl?NO??
分子量:	1147.44
類別:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用:	7-{[(2,2,2,-Trichloroethyl)oxy]carbonyl} Baccatin III (4S, 5S)-3-Benzoyl-2-(4-methoxyphenyl)-4-phenyl-5-oxazolidinecarboxylate can be obtained from (αS,βS)-β-Phenyl Isoserine Hydrochloride (P335435) which is an intermediate for the synthesis of Paclitaxel, Docetaxel and their derivatives. 7-{[(2,2,2,-Trichloroethyl)oxy]carbonyl} Baccatin III (4S, 5S)-3-Benzoyl-2-(4-methoxyphenyl)-4-phenyl-5-oxazolidinecarboxylate can also be used as reactant/reagent in synthetic preparation for semisynthesis of Paclitaxel by condensation of protected Baccatin III and synthetic C-13 side chain.
參考文獻	Duan, J., et al.: J. Med. Chem., 45, 4954 (2002); Ojima, I., et al.: Curr. Med. Chem., 6, 927 (1999); Shen, X., et al.: PCT Int. Appl., WOÂ2008074178 A1 20160626 (2016);

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