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| 產(chǎn)品編號：129240 |
| 產(chǎn)品名稱：泛昔洛韋, ≥99% |
| 產(chǎn)品CAS：104227-87-4 |
| 規(guī)格含量：50MG |
| 產(chǎn)品價(jià)格：2000 |
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| 產(chǎn)品詳細(xì)介紹 |
泛昔洛韋, ≥99%
Product Name： Famciclovir
別名:2-[2-(2-氨基-9H-嘌呤-9-基)乙基]-1,3-丙二醇二乙酯
CAS號:104227-87-4
分子式:C14H19N5O4
分子量:321.33
介紹： Famciclovir
貯存： 儲存溫度-20°C
可溶性：
DMSO 64 mg/mL
Water 64 mg/mL
Ethanol 48 mg/mL
生化和生理學(xué)機(jī)理：
Description： IC50 Value： Refer to penciclovir Famciclovir is the diacetyl 6-deoxy analog of the active antiviral compound penciclovir with potential use in the treatment of infections caused by the herpes family of viruses [1]. Famciclovir, a synthetic acyclic guanine derivative, is a prodrug which, after oral administration, is rapidly metabolised to the highly bioavailable antiviral compound penciclovir [2]. in vitro： Famciclovir induced rapid, dose-dependent suppression of viral replication and reduction in alanine aminotransferase (ALT), with greatest efficacy in the 500-mg tid treatment group. HBV DNA reduction was maintained throughout the treatment period. ALT also steadily declined during the treatment period [3]. in vivo： In rat, following dosing at 40 mg/kg, famciclovir was rapidly and extensively metabolized to the active antiviral compound penciclovir, which reached peak concentrations in the plasma (mean 3.5 micrograms/ml) at 0.5 h [4]. Necrotic hepatitis
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